Regenerative Ability of Immature Necrotic Permanent Teeth Using Different Scaffolds
NCT06693739 · Status: ACTIVE_NOT_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30
Last updated 2024-11-20
Summary
The goal of this clinical trial is to compare effect of different scaffolds on the regenerative potential of young permanent immature teeth with necrotic pulp. The main question it aims to answer is:
is there difference in regenerative potential using Hyaluronic acid and platelets rich fibrin as scaffolds in permanent immature teeth with necrotic pulp? participants will undergo regeneration protocol including hyaluronic acid and platelets rich fibrin as scaffolds Researchers will compare \[hyaluronic acid , platelets rich fibrin , and no scaffold \] to see the regenerative potential
Conditions
- Regeneration
Interventions
- PROCEDURE
-
Platelet rich fibrin
PRF membrane is placed as a scaffold inside the canal with no hyaluronic acid
- PROCEDURE
-
hyaluronic acid
hyaluronic acid gel is placed as a scaffold inside the canal with no PRF
- PROCEDURE
-
no scaffold
initiate bleeding using hand files size beyond apex with sharp strokes with no PRF or hyaluronic acid placed
Sponsors & Collaborators
-
Ain Shams University
lead OTHER
Principal Investigators
-
Mai Abdel Raouf, Teaching assistant · Ainshams University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 9 Years
- Max Age
- 20 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-12-20
- Primary Completion
- 2024-12-20
- Completion
- 2024-12-20
Countries
- Egypt
Study Locations
More Related Trials
-
Comparison Between Two Regenerative Scaffolds
NCT06227533 ·Status: COMPLETED ·Phase: NA
-
Demineralized Dentin Graft in Preservation of Post-Extraction Sites Associated With Delayed Implant Placement
NCT06251960 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Evaluation of Different Scaffolds in Regenerative Endodontic Treatment
NCT06945965 ·Status: COMPLETED ·Phase: NA
-
Hyaluronic Acid Gel in Ridge Preservation
NCT06176937 ·Status: COMPLETED ·Phase: PHASE4
-
Bi-layer Collagen Membrane Versus Subepithelial Connective Tissue Graft in the Treatment of Localized Gingival Recession
NCT07162207 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Treated Dentine Matrix and Platelet Rich Fibrin in Induction of Root Formation of Non-Vital Immature Permanent Teeth
NCT05775081 ·Status: COMPLETED ·Phase: NA
-
Clinical and Radiographic Evaluation of Indirect Pulp Capping Using Platelet Rich Fibrin Versus Mineral Trioxide Aggregate in Deep Carious Molars: a Randomized Controlled Trial
NCT06889363 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Injectable Platelet Rich Fibrin With Collagen Matrix in Treatment of Multiple Gingival Recession.
NCT05389059 ·Status: UNKNOWN ·Phase: NA
-
PRF and CGF Scaffolds With EDTA in Regeneration
NCT07265804 ·Status: COMPLETED ·Phase: NA
-
Comparing Microneedling and Injectable Platelet Rich Fibrin to Hyaluronic Acid In Papilla Reconstruction
NCT07280507 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
The Use of Adhesion Molecule Loaded Hydrogel With Minimally Invasive Surgical Technique in Treatment of Periodontal Intrabony Defect
NCT05653245 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Bovine Pericardium Membrane Versus Native Collagen Membrane in Conjunction With Sticky Bone Graft in Treatment of Class II Furcation Defects in Lower Molars.
NCT06681532 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Clinical and Radiographic Success Following Regenerative Pulpotomy Using Chitosan Hydrogel Versus Platelet Rich Fibrin in Mature Mandibular Molars
NCT06828978 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Palatal Wound Healing Evaluation After Application of Platelet Rich Fibrin Versus 0.2% Hyaluronic Acid Dressings
NCT04390100 ·Status: COMPLETED ·Phase: PHASE4
-
Comparative Evaluation of the Regenerative Capacity of Two Platelet Concentrates
NCT03698188 ·Status: UNKNOWN ·Phase: NA
-
Treatment of Deficient Interdental Papilla Using Albumin-platelets Rich Fibrin
NCT06842277 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Effect of Topical Application of Hyaluronic Acid on Stability of Immediate Loading Dental Implant in Posterior Maxilla
NCT05403099 ·Status: COMPLETED ·Phase: NA
-
Perforated Collagen Membrane With Nanohydroxyapatite for Intrabony Defects
NCT03399279 ·Status: COMPLETED ·Phase: NA
-
Ridge Preservation Using Collagen Sponge Alone or Combined with Xenograft: a Clinical and Histological Trial
NCT06896097 ·Status: COMPLETED ·Phase: NA
-
Efficacy of HA Gel Injection Versus Multilayer (L-PRF) in the Interdental Papilla Reconstruction
NCT05953896 ·Status: COMPLETED ·Phase: NA
-
Autogenous Dentin Derived Barrier Membrane Versus Collagen Membrane
NCT06615362 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Peri-implant Tissue Changes Using Dual Zone Concept with Connective Tissue Graft Versus Concentrated Growth Factor
NCT06728696 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
A Modern, Non-surgical Method for Treating Papillary Deficiencies is the Use of Hyaluronic Acid, Which Have Demonstrated Encouraging Outcome. Subperiosteal Hyaluronic Acid Injection Overlay Technique with the Idea of Merging Hyaluronic Acid Injection with Surgical Intervention to Reconstruct Idp
NCT06889311 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Gelatin Sponge VS PTFE Membrane for Socket Sealing After Immediate Implant Placement
NCT05982353 ·Status: COMPLETED ·Phase: PHASE1
-
Clinical Comparison of Xenograft With Hydrogel Versus Xenograft Alone in the Socket Preservation After Tooth Extraction: A Randomized Controlled Clinical Trial
NCT06957197 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3