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Correlation of Typical LBBB Mechanical Activation Pattern by 2D Strain Echocardiography With Acute GWE Improvement in Patients Receiving LBBp or Conventional BiVp for Cardiac Resynchronization Therapy (Echo LBBp)

NCT06689111 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2025-12-05

No results posted yet for this study

Summary

The present study is a multicenter interventional non randomised study in patients requiring an implantable device for cardiac resynchronization therapy. Its primary objective is to investigate whether the presence of a specific echocardiographic contraction pattern before implantation is associated with increased rates of acute improvement in myocardial function (as measured by an ultrasound) and to compare the improvement in two groups of patients based on the type of pacing (biventricular or left-sided pacing)

Conditions

  • Heart Failure With Reduced Ejection Fraction (HFrEF)

Interventions

DEVICE

Left bundle branch pacing lead

Use of LBBp Vs the standard method of BiVp in resynchronization therapy

DEVICE

CRT with the standard method through cs

standard CRT procedure

Sponsors & Collaborators

  • University General Hospital of Heraklion

    collaborator OTHER

  • Ippokrateio General Hospital of Thessaloniki

    collaborator OTHER

  • Onassis Cardiac Surgery Centre

    collaborator OTHER

  • Alexandra Hospital, Athens, Greece

    collaborator OTHER

  • Korgialenio-Benakio Red Cross Hospital

    collaborator OTHER

  • Ippokration General Hospital

    collaborator OTHER

  • University Hospital of Patras

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-23
Primary Completion
2026-09-30
Completion
2026-11-30
FDA Device
Yes

Countries

  • Greece

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06689111 on ClinicalTrials.gov