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Vitamin D Metabolites as Biomarkers for the Identification of Kidney Injury in Cardiac Surgery

NCT06688994 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 46

Last updated 2026-02-03

No results posted yet for this study

Summary

The investigators will be measuring vitamin D metabolites in blood samples drawn from patients undergoing cardiac surgery to determine the correlation with renal function as assessed by serum creatinine. The investigators will include 20 patients in each of the following 3 groups based on serum creatinine measured within 28-days of surgery: 1) normal kidney function (eGFR \> 60 mL/min, n=20), 2) moderate impaired kidney function, eGFR between 30 and 60 mL/min (n=20) and 3) severe kidney dysfunction eGFR \< 30 mL/min (n=20).

Conditions

  • Acute Kidney Injuries
  • Chronic Renal Diseases

Sponsors & Collaborators

  • University of Toronto

    collaborator OTHER

  • University Health Network, Toronto

    lead OTHER

Principal Investigators

  • Stuart A McCluskey, MD, PhD · University Health Network, Toronto

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-02
Primary Completion
2026-07-31
Completion
2026-12-31

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06688994 on ClinicalTrials.gov