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Beta-Cell - Liver Interactions in Situations of Modified Beta-Cell Function

NCT06682481 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2026-05-18

No results posted yet for this study

Summary

The investigators will measure blood levels of 1,5-anhydroglucitol in obese children with or without type 2 diabetes and correlate them with parameters related to functional beta-cell mass and glucose metabolism. The values will be compared to those obtained in healthy volunteers. The aim of the study is to test the validity of 1,5-anhydroglucitol as a novel biomarker of beta-cell mass and function in children with obesity with or without type 2 diabetes.

Conditions

  • Obesity, Childhood
  • Type 2 Diabetes Mellitus in Obese

Interventions

OTHER

Measurement of biomarker

Measurement of blood levels of 1,5-anhydroglucitol

Sponsors & Collaborators

  • University of Geneva, Switzerland

    collaborator OTHER

  • Philippe Klee, MD-PhD

    lead OTHER

Eligibility

Min Age
12 Years
Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-11-22
Primary Completion
2028-12-31
Completion
2028-12-31

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06682481 on ClinicalTrials.gov