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Deciphering AMD by Deep Phenotyping and Machine Learning- Prospective Study - SUMMIT (Part 2)

NCT06682455 · Status: ENROLLING_BY_INVITATION · Type: OBSERVATIONAL · Enrollment: 300

Last updated 2024-11-12

No results posted yet for this study

Summary

We will conduct a prospective, non-interventional roll-over extension of the PINNACLE study (Deciphering AMD by deep phenotyping and machine learning). This will include up to 300 intermediate AMD participants (= approximately 450 untreated intermediate AMD eyes, including both unilateral (AREDS IV) and bilateral (≥AREDS II)). As per the PINNACLE study, SUMMIT study participants will continue to be followed using OCT imaging every 4 months for a further 2-years, to specifically investigate the morphological sequence of events preceding the conversion towards late AMD. Across both studies combined, we will be able to detect the earliest focal sites of disease progression over a total 5-year follow-up.

Conditions

  • Age-Related Macular Degeneration

Sponsors & Collaborators

  • King's College London

    collaborator OTHER

  • Imperial College London

    collaborator OTHER

  • Medical University of Vienna

    collaborator OTHER

  • University of Michigan

    collaborator OTHER

  • University College, London

    collaborator OTHER

  • University Hospital, Basel, Switzerland

    collaborator OTHER

  • University of Southampton

    lead OTHER

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-06-12
Primary Completion
2027-06-30
Completion
2027-06-30

Countries

  • Austria
  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06682455 on ClinicalTrials.gov