MedTrace Logo

Transthoracic Echocardiographic Monitoring of Cardiac Output Effects of Colloid Preload and Crystalloid Coload During Cesarean Delivery Under Spinal Anesthesia

NCT06654687 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 162

Last updated 2025-05-21

No results posted yet for this study

Summary

Transthoracic echocardiography (TTE) has been introduced in anesthesia and intensive care practice to assess the volume status and predict fluid responsiveness, with a few studies performed on pregnant women (5).

In this study, we aim to evaluate the effect of intravenous administration of albumin as a colloid preload on the maternal stroke volume (SV) and cardiac output (CO) versus crystalloid coload. We used TTE to measure the changes in SV, and CO at baseline and at subsequent time points after spinal anesthesia.

Conditions

  • Pregnancy
  • Cesarean Delivery
  • Spinal Anesthesia Induced Hypotension
  • Cardiac Output Measurement
  • Volume Status

Interventions

DEVICE

Transthoracic Echocardiography

Transthoracic Echocardiography will be used to measure the changes in stroke volume and cardiac output.

DRUG

Ringer lactate 1000 ml

Patients will receive 1000 mL of Ringer's lactate solution over 15 minutes.

DRUG

Albumin

Patients will receive 250 mL of human albumin 5% over 10 minutes

DRUG

Ringer lactate 750 ml

Patients will receive 750 mL of Ringer's lactate solution over 15 minutes.

Sponsors & Collaborators

  • Sameh Fathy

    lead OTHER

Principal Investigators

  • MOHAMED TOLBA ELMORSY, MD · Lecturer of Anesthesia and ICU - Faculty of Medicine - Mansoura University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-10-27
Primary Completion
2025-02-15
Completion
2025-03-01

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06654687 on ClinicalTrials.gov