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Changes in Cardiac Output During Cesarean Delivery Under Spinal Anesthesia

NCT05269537 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 60

Last updated 2022-11-29

No results posted yet for this study

Summary

Cardiac output will be measured in healthy parturients undergoing cesarean delivery under spinal anesthesia

Conditions

  • Anesthesia, Spinal
  • Cesarean Section
  • Echocardiography
  • Cardiac Output

Interventions

RADIATION

Transthoracic Echocardiography

Measurement of cardiac output in supine position with left lateral tilt at baseline, at 10 minutes after intrathecal injection, immediately after delivery, and at 1 hour after intrathecal injection

PROCEDURE

Spinal Anesthesia

Performed at the L3-L4 or L4-L5 interspace using 25-gauge spinal needle

DRUG

Intrathecal Bupivacaine

Bupivacaine 12.5 mg (2.5 mL 0.5%) will be administered in the subarachnoid space

DRUG

Intrathecal Fentanyl

Fentanyl 15 μg will be administered in the subarachnoid space

DRUG

Crystalloid Coload 1000 mL

Ringer acetate 1000 mL will be administered over 10 minutes starting immediately after intrathecal injection

PROCEDURE

Cesarean Delivery

Lower segment cesarean section using the Pfannenstiel incision and uterine exteriorization

DRUG

Intravenous Ephedrine

Intravenous ephedrine 3, 5, and 10 mg will be administered when Systolic blood pressure decreases below 90%, 80%, and 70% of baseline, respectively.

DRUG

Oxytocin

Intravenous oxytocin 10 U in 500 mL Ringer acetate will be administered over 30 minutes starting immediately after delivery of the fetus

Sponsors & Collaborators

  • Mansoura University

    lead OTHER

Principal Investigators

  • Mohamed M Tawfik, MD · Department of Anesthesia and Surgical Critical Care, Mansoura University Hospitals, Mansoura, Egypt

Eligibility

Min Age
19 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-03-12
Primary Completion
2022-07-02
Completion
2022-07-02

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05269537 on ClinicalTrials.gov