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fMRI and Opioid Abstinence

NCT06651333 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 240

Last updated 2025-10-20

No results posted yet for this study

Summary

This project examines functional connectivity patterns associated with subsequent relapse to illicit opioids during treatment for OUD.

Conditions

  • Drug Use Disorder
  • Opioid Dependence
  • Opioid-Related Disorders
  • Opioid Use
  • Opioid Abuse

Interventions

DIAGNOSTIC_TEST

fMRI

Participants will be performing tasks while undergoing fMRI. Tasks include Stroop task, Emotion-regulation task and an Ambiguity reward task, Drug cue task, and Cognitive behavioral therapy task. Participants are not presented with any specific stimulus.

Sponsors & Collaborators

  • National Institute on Drug Abuse (NIDA)

    collaborator NIH

  • Yale University

    lead OTHER

Principal Investigators

  • Sarah Yip, PhD, MSc · Yale University

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-12-12
Primary Completion
2029-11-30
Completion
2029-11-30
FDA Device
Yes

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06651333 on ClinicalTrials.gov