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Ultrasound Guided Placental Growth Factor Vs Platelet Rich Plasma Injection in Peripheral Nerve Injury: an Interventional Study

NCT06638008 · Status: NOT_YET_RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2024-10-15

No results posted yet for this study

Summary

The goal of this clinical trial is to learn if placental growth factor injection and platelet rich plasma injection works to treat peripheral nerve injury in adults. and the role of nerve conduction study and neuromuscular ultrasound

The main questions it aims to answer are:

Does placental growth factor improve outcome after peripheral nerve injury? Does platelet rich plasma improve outcome after peripheral nerve injury? Researchers will compare drug both drugs to each other and will follow up the results via NCS and NMUS

Participants will be classified into 3 random groups:

one group will receive perineural injection of placental growth factor, the other group will receive peri neural PRP injection, third group will only be followed up without intervention Follow up of each patients will be done at 3 and 6 months

Conditions

  • Peripheral Nerve Injury Upper Limb

Interventions

DRUG

perineural injection

perineural intervention of placental growth factor in one group and PRP in other group

Sponsors & Collaborators

  • Assiut University

    lead OTHER

Principal Investigators

  • Essam Ahmed Abda, professor · professor of Rheumatology, Rehabilitation and physical medicine

  • Mohammed Raouf Abd El-razik, Assistant professor · Assistant professor of Rheumatology, Rehabilitation and physical medicine

  • Amira Mostafa El-sonbaty, lecturer · lecturer of Rheumatology, Rehabilitation and physical medicine

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-15
Primary Completion
2026-01-15
Completion
2028-03-01

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06638008 on ClinicalTrials.gov