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Comparison of Pulmonary Function, Exercise Capacity, and Physical Activity Level Between Children With Hemophilia and Healthy Controls

NCT06636565 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2025-09-10

No results posted yet for this study

Summary

Hemophilia is a rare X-linked congenital bleeding disorder characterized by deficiency of clotting factor VIII (hemophilia A) or deficiency of factor IX (hemophilia B) with complex diagnosis and management. Participation in physical activity is still limited in children with hemophilia, probably due to protective attitudes of families/patients and avoidance of activity, and possibly also as a result of chronic pain. Exercise capacity has been identified as a protective factor against joint problems in hemophilia. Aerobic fitness is associated with better pulmonary function in children. Chronic pain and decreased range of motion due to recurrent bleeding in joints and muscles in hemophilia may indirectly affect posture and respiratory mechanics, leading to impaired pulmonary function. This study aims to compare pulmonary function, exercise capacity, posture, and physical activity level between children with hemophilia and healthy controls and to investigate the relationship between these parameters.

Conditions

Interventions

OTHER

No intervention

No intervention

Sponsors & Collaborators

  • Hacettepe University

    lead OTHER

Principal Investigators

  • Aslihan Cakmak-Onal, PhD, PT · Hacettepe University

  • Ebru Calik-Kutukcu, PhD, PT · Hacettepe University

  • Hande Guney-Deniz, PhD, PT · Hacettepe University

  • Ş. Selin Aytac-Eyupoglu, MD · Hacettepe University

  • Firat Tan, MSc, PT · Ataturk University

Eligibility

Min Age
8 Years
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-07-25
Primary Completion
2025-07-25
Completion
2025-07-25

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06636565 on ClinicalTrials.gov