Remote Ischaemic Conditioning (RIC) in Heart Failure
NCT06616233 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2024-09-27
Summary
This study will test the impact of remote ischaemic conditioning combined with exercise on myocardial perfusion in patients with or at risk of heart failure
Conditions
- Heart Failure With Preserved Ejection Fraction
- Type 2 Diabetes
- Dilated Cardiomyopathy
Interventions
- DEVICE
-
Remote Ischaemic Conditioning with exercise
Participants will receive RIC through an automated device that will provide cycles on ischaemia/reperfusion to the target organ (arm). During the cuff deflation phase, participants will undergo handgrip exercise at 20-30% of their maximal voluntary contraction for 3 minutes. There will be a total of 4 cycles of exercise.
- DEVICE
-
Other: Remote Ischaemic Conditioning
Participants will receive RIC through an automated device that will provide cycles on ischaemia/reperfusion to the target organ (arm).. There will be a total of 4 cycles.
Sponsors & Collaborators
-
Loughborough University
collaborator OTHER -
University of Leicester
lead OTHER
Principal Investigators
-
Jayanth R Arnold, BMBCh DPhil · University of Leicester
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-04-08
- Primary Completion
- 2025-10-31
- Completion
- 2025-10-31
Countries
- United Kingdom
Study Locations
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