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Nitrate Mouth Rinse and the Oral Microbiome

NCT06588049 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2025-09-02

No results posted yet for this study

Summary

The study is aimed to determine if changes to the oral microbiome occur after the use of a nitrate rich mouth rinse. Participants with be asked to use either a controlled (water) mouthrinse once daily for 2 weeks while maintaining normal oral hygiene practices, or use the nitrate rich mouthrinse once daily for 2 weeks.

Primary Outcome measures:

-changes in the composition of the oral microbiome

Secondary Outcome measures

* Blood Pressure
* Salivary Nitric Oxide Levels

Conditions

  • Nitric Oxide
  • Oral Microbiome

Interventions

DIETARY_SUPPLEMENT

Beet Root

Beet Root powder used as a mouth rinse in suspension with water

OTHER

Water

Water used as a mouth rinse

Sponsors & Collaborators

  • Dalhousie University

    lead OTHER

Principal Investigators

  • Leigha Rock, PhD · Dalhousie University

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-08-14
Primary Completion
2025-05-16
Completion
2025-05-16

Countries

  • Canada

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06588049 on ClinicalTrials.gov