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Efficacy of Mouthwash in Reducing Salivary Carriage of COVID-19

NCT04603794 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2020-10-27

No results posted yet for this study

Summary

Researchers know that the virus that causes COVID-19 has been found in the saliva (spit) of individuals who exhibit signs of the disease. Investigators would like to test the ability of three mouthwashes to reduce the levels of this virus in participants' mouths. Investigators will ask participants to use a liquid to swish around in the mouth for 30 seconds and spit it into a collection cup. Investigators will also collect spit from participants before and after participants use the mouthwash. Although participants will have no direct benefits from the study, investigators will gain a wealth of information that would benefit patients who are at risk for COVID-19.

Conditions

Interventions

DRUG

0.5% Povidone Iodine

Commercially Available Mouth Rinses and Over the Counter Standard Formulations

DRUG

0.12% Chlorhexidine Gluconate Mouth Rinse

Commercially Available Mouth Rinses

DRUG

1% Hydrogen Peroxide

Commercially Available Over the Counter Standard Formulations USP (United States Pharmacopeia)

DRUG

0.9% Normal Saline

Commercially Available Over the Counter Standard Formulations USP (United States Pharmacopeia)

Sponsors & Collaborators

  • Ohio State University

    lead OTHER

Principal Investigators

  • David L Hall, DDS · The Ohio State University College of Dentistry

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-10-01
Primary Completion
2020-11-30
Completion
2020-11-30
FDA Drug
Yes

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04603794 on ClinicalTrials.gov