FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients
NCT06564389 · Status: RECRUITING · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 119
Last updated 2026-04-07
Summary
The purpose of the study is to evaluate the safety, tolerability, and pharmacokinetics of escalating single and repeat doses of PF-07832837 in healthy participants and in participants with moderate to severe atopic dermatitis. An additional goal is to assess the pharmacodynamics of PF-07832837 in participants with moderate to severe AD, including potential effects on clinical signs and symptoms
Conditions
- Healthy Participants
- Atopic Dermatitis
Interventions
- DRUG
-
PF-07832837
escalated doses of PF-07832837
- OTHER
-
Placebo
placebo
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Pfizer CT.gov Call Center · Pfizer
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 70 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-11-05
- Primary Completion
- 2027-06-02
- Completion
- 2027-06-02
- FDA Drug
- Yes
Countries
- United States
Study Locations
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