Clinical Effect, Safety and Tolerability of GSK1070806 in Atopic Dermatitis
NCT04975438 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 34
Last updated 2025-08-28
Summary
This study will evaluate efficacy and safety of GSK1070806 in moderate to severe atopic dermatitis (AtD) participants.
Conditions
- Dermatitis, Atopic
Interventions
- DRUG
-
GSK1070806
GSK1070806 will be administered
- DRUG
-
Placebo will be administered
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
GSK Clinical Trials · GlaxoSmithKline
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2021-11-18
- Primary Completion
- 2022-12-19
- Completion
- 2023-03-13
- FDA Drug
- Yes
Countries
- United States
- Canada
Study Locations
More Related Trials
-
Safety, Tolerability and PK of ATTO-3712 in Healthy Volunteers and Patients With Atopic Dermatitis
NCT07205081 ·Status: RECRUITING ·Phase: PHASE1
-
Study to Evaluate the Efficacy, Safety and Pharmacokinetics of ASB17061 Capsules in Adult Subjects With Atopic Dermatitis
NCT01756898 ·Status: COMPLETED ·Phase: PHASE2
-
A Study Evaluating APG777 in Atopic Dermatitis
NCT06395948 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Effect of OC000459 on Moderate to Severe Atopic Dermatitis
NCT02002208 ·Status: COMPLETED ·Phase: PHASE2
-
A Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 2 Doses of S-777469 in Patients With Atopic Dermatitis
NCT00703573 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Test Safety, Tolerability, and the Way the Body Absorbs, Distributes, and Gets Rid of a Study Drug Called MOR106, in Healthy Subjects and in Patients With Moderate to Severe Atopic Dermatitis
NCT03689829 ·Status: TERMINATED ·Phase: PHASE1
-
Topical NF-kappaB Decoy in the Treatment of Atopic Dermatitis
NCT00125333 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study to Evaluate the Effectiveness and Safety of Topical OPA-15406 Ointment to Treat Participants With Atopic Dermatitis
NCT02068352 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Safety and Tolerability of MOR106 Administered Concomitantly With Topical Corticosteroids, in Adult Participants With Moderate to Severe Atopic Dermatitis
NCT03864627 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis
NCT06130566 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase 1 Study of KHK4083 in Subjects With Atopic Dermatitis
NCT03096223 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Investigate the Efficacy and Safety of SHR-1905 in Patients With Moderate-to-severe Atopic Dermatitis
NCT07211542 ·Status: RECRUITING ·Phase: PHASE2
-
A Study to Evaluate the Safety and Efficacy of ATx201 in Subjects With Moderate Atopic Dermatitis
NCT03304470 ·Status: COMPLETED ·Phase: PHASE2
-
Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis
NCT06947993 ·Status: RECRUITING ·Phase: PHASE2
-
Efficacy and Safety Study of SHR-1819 Injection in Adult Patients With Severe Atopic Dermatitis
NCT06468956 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study to Assess the Efficacy and Safety of CMK389 in Patients With Moderate to Severe Atopic Dermatitis.
NCT04836858 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety Study of SHR-1819 Injection in Adult Patients With Severe Atopic Dermatitis
NCT05549947 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of JNJ-95597528 in Participants With Moderate to Severe Atopic Dermatitis
NCT07230860 ·Status: RECRUITING ·Phase: PHASE2
-
Study to Evaluate Safety and Tolerability of PF-07242813 in Healthy Participants and Participants With Atopic Dermatitis
NCT04668066 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase 1/1b Study to Evaluate Safety, Tolerability and Pharmacokinetics of ZL-1503 in Healthy Volunteers and Participants With Moderate to Severe Atopic Dermatitis
NCT07235384 ·Status: RECRUITING ·Phase: PHASE1
-
A Study to Determine the Safety & Efficacy of ZPL-5212372 in Healthy Subjects and in Subjects With Atopic Dermatitis
NCT02795832 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of LW402 in Moderate-to-Severe Atopic Dermatitis
NCT07186387 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of MEDI3506 in Adult Subjects With Atopic Dermatitis
NCT04212169 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluate Efficacy and Safety of Oral SHR0302 in Subjects Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis
NCT04875169 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Evaluate the Safety, Tolerability, Drug Levels, and Drug Effects of BMS-986326 in Participants With Atopic Dermatitis
NCT06248814 ·Status: COMPLETED ·Phase: PHASE1