MedTrace Logo

Effect of Albumin Replacement on Oxygen Delivery in Sepsis Patients

NCT06556914 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 45

Last updated 2025-07-03

No results posted yet for this study

Summary

Fluid resuscitation is a critical component of sepsis treatment. Research has shown that intravenous (IV) fluid therapy in sepsis positively impacts cardiac output and thereby oxygen (O2) delivery through a complex interaction of central venous pressure, right atrial pressure, venous resistance, ventricular compliance, cardiac contractility, and systemic vascular resistance. The 2021 sepsis prevention guidelines recommend balanced crystalloids as first-line therapy. However, no studies in the literature have evaluated the effect of albumin on O2 delivery. In our study, the investigators aim to assess the impact of albumin replacement on O2 delivery in sepsis patients in the intensive care unit.

Conditions

Sponsors & Collaborators

  • Samsun University

    lead OTHER

Principal Investigators

  • gamze MD ertaş, specialist · Samsun University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-11-15
Primary Completion
2025-10-01
Completion
2025-10-15

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06556914 on ClinicalTrials.gov