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MicroRNAs and Prognosis in Breast Cancer

NCT06555354 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1432

Last updated 2024-08-15

No results posted yet for this study

Summary

Mono-centric, observational retrospective and prospective study, designed for breast cancer patients to identify novel miRNA based biomarker able to predict metastases development in breast cancer patients.

Conditions

  • Breast Cancer Female
  • Metastases Breast

Interventions

DIAGNOSTIC_TEST

miRNA targeted analysis on breast cancer tissues

Total RNA is extracted from tissue sample and selected miRNA quantified by PCR based relative quantification method (QPCR) with a standard curve.

DIAGNOSTIC_TEST

miRNA targeted analysis on plasma samples

miRNAs extracted from plasma samples are analysed by QPCR and/or ddPCR .

DIAGNOSTIC_TEST

miRNA profiling of breast cancer tissues

Selected samples from the retrospective cohort are profiled for miRNA expression by using GeneChip® miRNA 4.0 Array.

Sponsors & Collaborators

  • Casa Sollievo della Sofferenza IRCCS

    lead OTHER

Eligibility

Min Age
18 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-10-28
Primary Completion
2018-10-28
Completion
2019-11-28

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06555354 on ClinicalTrials.gov