miRNA and Relevant Biomarkers of BC Patients Undergoing Neoadjuvant Treatment
NCT03779022 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2019-08-28
Summary
MicroRNA (miRNA) is a type of endogenous non-coding RNA. They are responsible for post-transcriptional regulation and participate in many vital biological processes. Expression profiling has shown that miRNAs can distinguish between normal breast and tumor tissues. In recent years, circulating miRNAs have become promising biomarkers based on their stability and their non-invasive testing and feasibility in clinical practices.
Conditions
Interventions
- GENETIC
-
microRNA
The level of microRNA in plasma will be detected by TaqMan in screening phase and by quantitative Real-time PCR (qRT-PCR) in validation phase.
Sponsors & Collaborators
-
Cui Yimin
lead OTHER
Principal Investigators
-
Yimin Cui, Ph.D & M.D · Peking University First Hospital
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-11-01
- Primary Completion
- 2019-09-30
- Completion
- 2019-12-31
Countries
- China
Study Locations
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