The FDA granted Breakthrough Device Designation to TOBY Inc.'s urine-based Alzheimer's diagnostic test and Instanosis Inc.'s Xylazine Rapid Test (Urine), accelerating development of both non-invasive diagnostic technologies.
The blood-brain barrier continues to block most treatments for glioblastoma and central nervous system diseases, with only 0.01% of biologic drugs reaching the brain. New intellectual property coverage and synthetic methods aim to address delivery challenges.
Insilico Medicine has formed a strategic partnership with Liquid AI to develop lightweight scientific foundation models for drug discovery and entered a drug development collaboration with China Medical System Holdings targeting CNS and autoimmune diseases.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07451769 |
Selective Activation of the Adrenomedullin Receptors in Migraine |
NOT_YET_RECRUITING | NA |
| NCT07340788 |
Amylin-Induced Migraine Attacks Without Aura |
NOT_YET_RECRUITING | NA |
| NCT07340775 |
Hypersensitivity to Amylin in Post-Traumatic Headache |
NOT_YET_RECRUITING | NA |
| NCT07335185 |
Gravity Stroke System for Recanalization of Large Vessel Occlusion Strokes |
NOT_YET_RECRUITING | NA |
| NCT07326566 |
Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII |
RECRUITING | PHASE2 |
| NCT07324330 |
Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity |
RECRUITING | NA |
| NCT07313098 |
Longitudinal Assessment of Protein Markers in the Cerebrospinal Fluid of Patients With Central Nervous System Involvement |
NOT_YET_RECRUITING | |
| NCT07288385 |
Investigating the Feasibility of Combining Virtual Reality and Bilateral Transcranial Direct Stimulation to Improve Upper Limb Recovery in Patients With Stroke |
RECRUITING | NA |
| NCT06993142 |
Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage |
NOT_YET_RECRUITING | NA |
| NCT06954610 |
Cardiac Assessment for Recurrent Stroke Risk Evaluation in Atrial Fibrillation |
RECRUITING |
