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Cardiovascular Response to Isometric BFR Exercise

NCT06529068 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 21

Last updated 2025-06-12

No results posted yet for this study

Summary

The goal of this interventional study is to evaluate the acute impact of isometric blood flow restriction (BFR) exercise on blood pressure and other cardiovascular functions in healthy young adult volunteers. The main question it aims to answer is:

The investigators hypothesize that isometric BFR exercise with a wide-rigid cuff would lead to greater blood pressure and other cardiovascular responses and that these cardiovascular responses would be greater under isometric BFR exercise with narrow-elastic bands compared with the control condition (no cuff).

Participants will perform isometric exercises in 3 laboratory visits with different exercise conditions) no cuff control 2) BFR with wide-rigid cuff 3) BFR with narrow-elastic band.

Conditions

  • Blood Pressure

Interventions

BEHAVIORAL

Isometric handgrip exercise

The participants will perform isometric handgrip exercises without blood flow restriction.

BEHAVIORAL

Isometric handgrip exercise with a narrow-elastic band

The participants will perform isometric handgrip exercises with blood flow restriction using a narrow-elastic band.

BEHAVIORAL

Isometric handgrip exercise with a wide-rigid cuff

The participants will perform isometric handgrip exercises with blood flow restriction using a wide-rigid cuff.

Sponsors & Collaborators

  • University of Texas at Austin

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-12-02
Primary Completion
2025-05-30
Completion
2025-05-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06529068 on ClinicalTrials.gov