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Resveratrol-Based Gel Application in a Palatal Wound Following Free Gingival Graft Surgery

NCT06521333 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-03-17

No results posted yet for this study

Summary

Aim of the study to compare the effect of Resveratrol- Based gel versus 0.2% Hyaluronic acid gel applied to the palatal donor site and acrylic resin stent only in post-operative pain reduction after free gingival graft harvesting.

Conditions

  • Mucogingival Defects

Interventions

DRUG

Resveratrol-Based gel

The Resveratrol-Based gel will be applied using a sterile plastic syringe, and the palatal wound will be immediately covered by an acrylic resin stent. Three days postoperatively, the patients will be recalled, the stent will be removed for evaluation and the Resveratrol gel will be reapplied.

DRUG

Hyaluronic acid gel 0.2%

The 0.2% Hyaluronic acid gel will be applied using a sterile plastic syringe, and the palatal wound will be covered by an acrylic resin stent. Three days postoperatively, the patients will be recalled, the stent will be removed for evaluation, and the Hyaluronic acid gel will be reapplied.

DEVICE

Stent

The palatal wound will be immediately covered by acrylic resin stent three days postoperatively, the patients will be recalled, and the stent will be removed for evaluating the healing of the palatal wound and then recover with stent.

Sponsors & Collaborators

  • Cairo University

    lead OTHER

Principal Investigators

  • Liza S ALhakam · master student.

  • Manar T El-Zanaty, PhD · Lecturer of oral medicine and Periodontology, Faculty of Dentistry, Cairo University.

  • Enji A Mahmoud, Professor · Professor of Oral Medicine and Periodontology, Faculty of Dentistry, Cairo University.

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-05-14
Primary Completion
2025-12-30
Completion
2026-01-01

Countries

  • Egypt

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06521333 on ClinicalTrials.gov