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Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part III

NCT04865952 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 8

Last updated 2022-10-04

No results posted yet for this study

Summary

The purpose of the present study is to evaluate the effect of Hyaluronic acid application in the gene expression profile and cellular behavior in the early wound healing process -24 hours after injury- of the oral soft tissues.

Conditions

  • Wound Heal
  • Wound Surgical
  • Oral Soft Tissue Conditions
  • Hyaluronic Acid

Interventions

PROCEDURE

periodontal surgery + 24 hr buccal attached gingiva (G) biopsy

Periodontal surgery will be performed and 24 hr after the surgical procedure a 2mm punch biopsy will be harvested at the level of the buccal attache gingiva (G).

OTHER

HA application

HA will be applied at the end of the surgical procedure, at the level of the vertical released incisions (VRIs) and over VRIs

Sponsors & Collaborators

  • University of Roma La Sapienza

    lead OTHER

Principal Investigators

  • Andrea Pilloni, MD,DDS,MS · University of Roma La Sapienza

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
30 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-04-29
Primary Completion
2021-07-05
Completion
2021-07-06

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04865952 on ClinicalTrials.gov