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Neural Computations of Goal-directed Decision-making

NCT06489561 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2025-07-18

No results posted yet for this study

Summary

The purpose of this research is to better understand how the human brain accomplishes the cognitive task of making goal-directed decisions. These investigations are critical to better understand human cognition and to design treatments for disorders of decision making and performance monitoring.

Conditions

  • Epilepsy Intractable

Interventions

BEHAVIORAL

Cedrus RB-844 response pad; Adtech Behnke-Fried micro-electrodes; Neurolynx electrophysiology system

Devices listed are components of a single intervention that includes: Record patient responses (Cedrus RB-844), record neuronal activity (Neurolynx) from electrodes (Adtech Behnke-Fried)

Sponsors & Collaborators

  • National Institute of Mental Health (NIMH)

    collaborator NIH

  • California Institute of Technology

    collaborator OTHER

  • Cedars-Sinai Medical Center

    lead OTHER

Principal Investigators

  • Ueli Rutishauser, PhD · Cedars-Sinai Medical Center

  • Adam Mamelak, MD · Cedars-Sinai Medical Center

  • John O'Doherty, PhD · California Institute of Technology

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-08-01
Primary Completion
2028-07-01
Completion
2028-07-01

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06489561 on ClinicalTrials.gov