MedTrace Logo

Olive Leaf Extract, Meta-inflammation, Anxiety, and Excess Weight

NCT06485349 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2024-10-18

No results posted yet for this study

Summary

Excess Weight is accompanied by a process that produces a low-grade inflammation state, called meta-inflammation. Anxiety is also associated with inflammation. Inflammation is closely related to oxidative stress. Both processes help perpetuate each other. Olive Leaf Extract (OLE) is known for having anti-inflammatory and antioxidant effects; by this means, its anxiolytic effect has been proved in animal models. The purpose of this investigation is to evaluate the anti-inflammatory and anxiolytic effects associated with the supplementation of OLE at a daily dose of 750mg (20% oleuropein) for 3 months.

Conditions

  • Women
  • Excess Weight
  • Anxiety Disorders

Interventions

DIETARY_SUPPLEMENT

Olive Leaf Extract (OLE)

Daily dose of 750mg OLE consumed with water after breakfast without any modification of their dietary patterns for 90 days.

OTHER

Placebo

100mg microcrystalline cellulose

Sponsors & Collaborators

  • University of Guadalajara

    lead OTHER

Principal Investigators

  • Ma. Sonia Luquin, Ph.D · University of Guadalajara

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-10-16
Primary Completion
2025-11-30
Completion
2026-01-31

Countries

  • Mexico

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06485349 on ClinicalTrials.gov