A Study to Assess Serotonin Transporter Occupancy of Healthy Adults Using 11C-DASB PET
NCT06476509 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2025-06-10
Summary
This study was a non-randomized, open-label clinical study to assess Serotonin transporter occupancy in the brain of healthy adults using 11C-DASB positron emission tomography (PET)
Conditions
Interventions
- DRUG
-
LV232 40mg
oral
- DRUG
-
Escitalopram 20 mg
oral
- DRUG
-
LV232 60mg
oral
- DRUG
-
LV232 20mg
oral
Sponsors & Collaborators
-
Vigonvita Life Sciences
lead INDUSTRY
Principal Investigators
-
Yifeng SHEN, MD · Shanghai Mental Health Center
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-05-30
- Primary Completion
- 2025-01-19
- Completion
- 2025-05-23
Countries
- China
Study Locations
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