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The Influence of Menopausal Status on Myocardial Stiffness and Exercise Capacity Among Female Masters Endurance Athletes.

NCT06475768 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2025-11-06

No results posted yet for this study

Summary

The purpose of this research is to study postmenopausal female masters athletes to see if they will show greater myocardial stiffness and reduced exercise capacity than premenopausal females and similarly aged male masters athletes.

Conditions

  • Myocardial Stiffness

Interventions

DIAGNOSTIC_TEST

Stress Echocardiogram

Exercise testing via treadmill with simultaneous gas exchange analysis and pre- and post-exercise transthoracic echocardiography.

DIAGNOSTIC_TEST

Cardiovascular Magnetic Imaging (cMRI)

Non-invasive imaging scan used to examine function and structure of the heart

DIAGNOSTIC_TEST

Cardiac Magnetic Resonance Elastography (cMRE)

Non-invasive imaging scan used to measure myocardial stiffness

Sponsors & Collaborators

Principal Investigators

  • Kathryn Larson, MD · Mayo Clinic

Eligibility

Min Age
40 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-09-14
Primary Completion
2025-10-06
Completion
2025-10-06

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06475768 on ClinicalTrials.gov