Biomarkers and Imaging Markers for ICH
NCT06462274 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2024-06-17
Summary
Intracerebral hemorrhage (ICH) is a subtype of stroke associated with high mortality and disability. Basic and clinical research has contributed to our understanding of the complex pathophysiology in ICH. However, questions regarding acute diagnosis, therapeutic decisions, and prognostication of ICH remain unanswered. Molecular biomarkers and imaging markers have revolutionalized diagnosis and treatment of many diseases, such as troponin use in myocardial infarction and magnetic resonance imaging (MRI) scan in ischemic stroke. Therefore, the investigators aim to discovery the potential biomarkers by screening samples of blood, cerebral spinal fluid, urine, saliva, and even tissues (if available) from ICH patients, and imaging markers via serial multimodality imaging scans such as computed tomography(CT), magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS), positron emission tomography (PET), etc. These molecular and imaging markers would assist in contributing additional information to current tools for onset warning, diagnosis, therapy monitoring, risk stratification, intervention and prognosis for ICH patients.
Conditions
- Intracerebral Hemorrhage
Interventions
- OTHER
-
body sample collection and imaging scan
Sponsors & Collaborators
-
Southwest Hospital, China
lead OTHER
Principal Investigators
-
Rong Hu, Ph.D · Southwest Hospital, China
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2014-01-01
- Primary Completion
- 2026-06-01
- Completion
- 2026-12-01
Countries
- China
Study Locations
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