Position Intervention to Reduce Hypoxemia in Sedation Patients

Summary

Hypoxemia was defined as an SpO2 of \< 90% for any duration. Failure to treat promptly can lead to hypoxemia, which may increase the risks of arrhythmia, nausea and vomiting, and cognitive dysfunction. Studies have shown that body position has a direct impact on respiratory function. In special environments, including outside the operating room where emergency airway management for critically ill and injured patients is needed, or in areas with limited medical resources like remote areas, adopting simple interventions by changing position to maintain patients' respiratory function can be more economical, convenient and safe.

Conditions

• Hypoxemia
• Sedation Complication
• Emergencies
• Airway Remodeling

Interventions

OTHER

The position adopted when patients undergoing procedure or surgery

For patients requiring sedation for procedures or surgery, they are randomly assigned either to supine position or lateral position before they are sedated, and kept during procedure or surgery.

Sponsors & Collaborators

• Zhejiang Provincial Tongde Hospital

  collaborator OTHER

• Shenzhen Second People's Hospital

  collaborator OTHER

• Zhejiang Provincial People's Hospital

  collaborator OTHER

• The Sixth Affiliated Hospital of Wenzhou Medical University

  collaborator OTHER

• Lishui Municipal Central Hospital

  collaborator OTHER_GOV

• Ningbo No. 1 Hospital

  collaborator OTHER

• Zunyi Medical College

  collaborator OTHER

• The First Affiliated Hospital of Zhengzhou University

  collaborator OTHER

• First Affiliated Hospital of Zhejiang University

  lead OTHER

Principal Investigators

• Xiangming Fang, M.D. · Zhejiang University

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2024-06-20

Primary Completion

2026-05-31

Completion

2026-06-30

Countries

• China

Study Locations