Relationship Between Circulating Sclerostin and Bone Lesions in Patients With Mastocytosis
NCT06440148 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50
Last updated 2024-06-03
Summary
Mastocytosis is very rare and highly heterogeneous group of disorders, characterized by the accumulation of clonal mast cells which can infiltrate several organs and tissues.
Bones are the most frequent localization of systemic mastocytosis. The aim of our research was to explain the potential role of sclerostin in the pathogenesis of bone disease in mastocytosis.
Conditions
- Mastocytosis
- Bones
Interventions
- BIOLOGICAL
-
SCLEROSTIN
Pathogenesis of mastocytosis bone disease
Sponsors & Collaborators
-
Medical University of Lublin
lead OTHER
Principal Investigators
-
Aneta A Szudy-Szczyrek, MD., PhD. · Medical University of Lublin
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2019-09-01
- Primary Completion
- 2024-05-01
- Completion
- 2026-12-31
Countries
- Poland
Study Locations
More Related Trials
-
Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in 17p- Chronic Lymphocytic Leukemia (CLL)
NCT01675102 ·Status: COMPLETED
-
Normal Blood, Bone Marrow and Buccal Mucosa Protocol
NCT00806364 ·Status: COMPLETED
-
Mesenchymal Stem Cell Based Therapy for the Treatment of Osteogenesis Imperfecta
NCT02172885 ·Status: COMPLETED ·Phase: PHASE1
-
Diagnostic Value of Bone Marrow Tryptase in Systemic Mastocytosis
NCT02441166 ·Status: COMPLETED ·Phase: NA
-
Questionnaire and Tissue Banking For Multiple Myeloma, Waldenstrom Macroglobulinemia and Related Disorders
NCT01177527 ·Status: ACTIVE_NOT_RECRUITING
-
MSC and HSC Coinfusion in Mismatched Minitransplants
NCT01045382 ·Status: TERMINATED ·Phase: PHASE2
-
Mesenchymal Stem Cell Therapy for Lung Rejection
NCT02181712 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Pulmonary MRI for the Diagnosis of Bronchiolitis Obliterans Syndrome After Allogeneic Stem Cell Transplantation
NCT04080232 ·Status: COMPLETED ·Phase: NA
-
Ohio State University Multiple Myeloma and Amyloidosis Data Registry and Sample Resource
NCT01408225 ·Status: RECRUITING
-
Respiratory Microbioma and Respiratory Complications After Hematopoietic Stem Cell Transplantion
NCT06639750 ·Status: NOT_YET_RECRUITING
-
Mesenchymal Stem Cells for Treatment of Poor Graft Function After Allogeneic Hematopoietic Stem Cell Transplantation
NCT06171906 ·Status: NOT_YET_RECRUITING ·Phase: PHASE4
-
Study Through Imaging of Visceral Lymphoid Organs in Patients With SCID Who Have Recieved Bone Marrow Allograft
NCT04246840 ·Status: COMPLETED
-
MSCs Combined With CD25 Monoclonal Antibody and Calcineurin Inhibitors for Treatment of Steroid-resistant aGVHD
NCT02241018 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Umbilical Cord Derived Mesenchymal Stem Cells Transplantation for Active and Refractory Systemic Lupus Erythematosus
NCT01741857 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
Children, Adolescents and Young Adults with Myeloproliferative Neoplasia: Study of Clinico-biological Characteristics and Complications (VYP)
NCT06715267 ·Status: RECRUITING
-
Hematogenous Osteomyelitis in Childhood Can Relapse Dozens of Years in Adulthood
NCT03898219 ·Status: COMPLETED
-
Research Study in Healthy Volunteers of Patients With Fanconi Anemia, Myeloproliferative Disorders, or Myeloma
NCT00900055 ·Status: COMPLETED
-
Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders
NCT01758042 ·Status: COMPLETED ·Phase: NA
-
Unrelated Donor Transplant for Malignant and Non-Malignant Disorders
NCT01050439 ·Status: TERMINATED ·Phase: PHASE2
-
Aquagenic Pruritus in Myeloproliferative Neoplasms
NCT04018209 ·Status: COMPLETED
-
Improving Blood Stem Cell Collection and Transplant Procedures
NCT01517035 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Constitution of a Biological Cohort Following Bone Marrow Sampling From MDS or AML Patients and Age-matched Healthy Donors
NCT03233074 ·Status: TERMINATED
-
Study on the Impact of Stem Cell Donation and Bone Marrow Harvesting on Unrelated Donors
NCT01884610 ·Status: COMPLETED
-
Longitudinal Data Registry of Plasma Cell Dyscrasia
NCT06760052 ·Status: RECRUITING
-
Properties of Mesenchymal Stem Cells in Lung Transplant
NCT01668576 ·Status: TERMINATED