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The Association Between Respiratory Effort Parameters During the First 48 Hours With Clinical Outcomes in Mechanically Ventilated Patients: A Prospective Observational Study.

NCT06433076 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 163

Last updated 2024-05-29

No results posted yet for this study

Summary

Over-assisted mechanical ventilation (MV) is linked to respiratory muscle disuse atrophy, while under-assisted MV can lead to patient self-inflicted lung injury (P-SILI) or respiratory muscle injuries. Both scenarios result in poor outcomes. This hypothesis aims to demonstrate the association between the degree of respiratory effort which was measured by P0.1, predicted Pmus, and predicted Δtranspulmonary pressure (ΔPL) with ventilator-free days (VFD) and 28-day mortality.

Conditions

  • Respiratory Effort
  • Respiratory Distress Syndrome
  • Lung Mechanics

Sponsors & Collaborators

  • Ramathibodi Hospital

    lead OTHER

Principal Investigators

  • Mr. Phruet Soipetkasem, Critical care doctor · Doctor of Critical care medicine Ramathibodi hospital

  • Pongdhep Theerawit, Assoc. Prof. · Head of Critical care medicine Ramathibodi hospital

  • Yuda Sutherasan, Assoc. Prof. · Clinical professor of Pulmonary and Critical care medicine Ramathibodi hospital

  • Mr. Detajin Junhasavasdikul, Asst.Prof. · Clinical professor of Pulmonary and Critical care medicine Ramathibodi hospital

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-06-08
Primary Completion
2024-03-31
Completion
2024-04-30

Countries

  • Thailand

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06433076 on ClinicalTrials.gov