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Exploration of Mechanisms for Weaning Failure

NCT06424314 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2024-07-09

No results posted yet for this study

Summary

This study is a prospective physiologic study. The primary study population will be adult invasive tracheal intubated patients with COPD, and investigators will collect relevant demographic data, vital signs, and baseline physiologic parameters of the patients prior to the spontaneous breathing test（SBT).

The participants will be divided into a successful withdrawal group and a failed withdrawal group according to the SBT outcome, and the changes in the above parameters during SBT will be compared between the two groups .

Conditions

  • Weaning Failure
  • Central Respiratory Depression
  • Diaphragm Injury
  • Phrenic Nerve Disorder

Interventions

DIAGNOSTIC_TEST

Monitoring of respiratory mechanics parameters

Physiologic recording instrumentation measure maximal transdiaphragmatic pressure，twitch diaphragmatic pressure and maximal diaphragmatic electromyography

Sponsors & Collaborators

  • The First Affiliated Hospital of Guangzhou Medical University

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-07-09
Primary Completion
2025-07-01
Completion
2025-12-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06424314 on ClinicalTrials.gov