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Prospective Clinical Trial for Children With TCRαβ Depleted vs Traditional Haplo Identicle HSCT

NCT06423131 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 110

Last updated 2024-05-29

No results posted yet for this study

Summary

This is a single-center prospective, non-randomized controlled clinical study in China using CliniMACS TCRα/β+ cell depleted stem cell haploidentical donors versus conventional Beijing protocol for haploidentical hematopoietic stem cell transplantation in children.

Conditions

  • Graft-Versus-Host Disease
  • Hematopoietic Stem Cell Transplantation
  • Child, Only
  • Haploidentical Hematopoietic Stem Cell Transplantation

Interventions

PROCEDURE

TCRαβ Depleted haploidentical HCT

Use the CliniMACS TCRα/β deplete from the mobilized peripheral blood stem cells of haploidentical donor in children

Sponsors & Collaborators

  • Sijia Gu

    lead OTHER

Principal Investigators

  • Jing Chen, PhD · Shanghai Children's Medical Center

Study Design

Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
8 Weeks
Max Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-26
Primary Completion
2027-03-31
Completion
2028-03-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06423131 on ClinicalTrials.gov