Exploratory Study of Precise Therapy for Advanced Tumor Patients With Malignant Hydrothorax or Ascites by Using PTC Drug Sensitivity Testing
NCT06413212 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 55
Last updated 2025-06-04
Summary
To explore the consistency between result of PTC drug screening tests and actual clinical outcome for patients with advanced malignancy.
Conditions
Interventions
- DIAGNOSTIC_TEST
-
Patient-derived tumor-like cell clusters (PTC) drug sensitivity testing.
Fresh malignant effusion samples were collected from advanced malignancy patients for PTC drug sensitivity testing, then assess the accuracy of this diagnostic test by combination and analysis with final clinical outcome.
Sponsors & Collaborators
-
Beijing GeneX MedLab Co., Ltd
collaborator INDUSTRY -
Liu Huang
lead OTHER
Principal Investigators
-
Liu Huang · Tongji Hospital
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2023-08-04
- Primary Completion
- 2025-12-31
- Completion
- 2025-12-31
Countries
- China
Study Locations
More Related Trials
-
A Study of DC05F01 in Chinese Patients with Advanced or Metastatic Solid Tumors
NCT06873542 ·Status: COMPLETED ·Phase: PHASE1
-
Chemotherapy Combined With Immunotherapy in HER 2 Insertion or Amplification Advanced NSCLC
NCT04324125 ·Status: RECRUITING
-
A Study of Continuous Endostar Intravenous Infusion Combined With Pemetrexed and Carboplatin in Advanced Non Small Cell Lung Cancer Patients
NCT01531790 ·Status: COMPLETED ·Phase: PHASE1
-
To Evaluate the Efficacy and Safety of Anlotinib Hydrochloride Capsule in Postoperative Non-pCR Patients With Non-small Cell Lung Cancer
NCT06352008 ·Status: RECRUITING ·Phase: PHASE2
-
Study of Apatinib and MASCT in Patients With Advanced Solid Tumors
NCT02844881 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Study of PM1022 in Patients With Advanced Tumors
NCT05867771 ·Status: UNKNOWN ·Phase: PHASE1/PHASE2
-
A Study of Trilaciclib Combined With Chemotherapy in the Treatment of NSCLC
NCT06328049 ·Status: RECRUITING ·Phase: PHASE2
-
PTC-Guided Therapy for Peritoneal Mesothelioma
NCT07330271 ·Status: RECRUITING ·Phase: NA
-
A Real-world Study of the Efficacy and Safety of PD-1 Inhibitors Combined With Chemoradiotherapy in Lung Metastatic Nasopharyngeal Carcinoma
NCT07062484 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Efficacy of Argon-Helium Cryoablation Plus PD-1 Inhibitors in NSCLC
NCT07053215 ·Status: COMPLETED ·Phase: NA
-
A Phase I Study of NK042 Cell Injection in Advanced Solid Tumors
NCT06773091 ·Status: RECRUITING ·Phase: PHASE1
-
Efficacy and Safety Study of Medical Thoracoscope Cryotherapy Combined Standard First-line Treatment of Advanced Non-small Cell Lung Cancer and Malignant Pleural Effusion
NCT05291403 ·Status: UNKNOWN ·Phase: NA
-
Concurrent Chemoradiotherapy Combination With Anlotinib for Unresectable Stage III NSCLC Patients
NCT03672136 ·Status: UNKNOWN ·Phase: PHASE2
-
Study of MHB088C for Patients With Advanced Solid Malignant Tumors
NCT07102004 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Clinical Study to Evaluate the Safety and Tolerability of AWT020 in Patients With Advanced Malignancies
NCT06839105 ·Status: RECRUITING ·Phase: PHASE1
-
The Clinical Study of Modern Therapies on Flora in Body Fluids and Blood of Malignant Tumor Patients
NCT04202848 ·Status: UNKNOWN
-
Anti-PD-1 in Combination With Chemotherapy as First-Line Treatment to Lung Cancer
NCT03432598 ·Status: COMPLETED ·Phase: PHASE2
-
Aims to Explore the Safety, Tolerability, and Preliminary Efficacy of SCTB41 in Adult Patients with Advanced Malignant Solid Tumours.
NCT06600022 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Clinical Study on the Second-line and Above Treatment of Advanced Solid Tumor With Anlotinib Combined With Pd-1 Antibody
NCT03975036 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Bronchoscopic Cryoablation Combined With Chemo-Immunotherapy in NSCLC With Central Airway Obstruction
NCT06604351 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
PLATFORM Study of Precision Medicine for Rare Tumors
NCT04423185 ·Status: RECRUITING ·Phase: PHASE2
-
Predictive Biomarker for Efficacy and Safety of Combination of Chemotherapy and Tislelizumab in NSCLC
NCT05244837 ·Status: UNKNOWN ·Phase: PHASE2
-
A Safety and Efficacy Trial of Docetaxel With or Without XH1 in Non-small Cell Lung Cancer (NSCLC) Patients
NCT03407300 ·Status: UNKNOWN ·Phase: PHASE2
-
Study to Investigate the Absorption, Metabolism and Excretion of [14C] Anlotinib in Patients With Advanced Cancer Patients
NCT02622932 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Chemotherapy on TMB in NSCLC
NCT03683407 ·Status: UNKNOWN