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Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure

NCT06406725 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2026-05-06

No results posted yet for this study

Summary

The goal of this prospective, observational study is to evaluate for the presence of vocal fold motion impairment (VFMI) in the children admitted to the pediatric intensive care unit on noninvasive positive pressure ventilation (NIV PPV). Participants will have two ultrasounds of their vocal folds performed, once while on NIV PPV and once after weaned off of the NIV PPV. This results of these scans will be reviewed against one another and against the gold standard, fiberoptic nasolaryngoscopy (FNL). The main question this study aims to answer is: Can POCUS be used to reliably detect VFMI while pediatric patients on supported with NIV PPV?

Conditions

  • Vocal Cord Dysfunction
  • Vocal Cord Paralysis
  • Vocal Cord Paresis
  • Recurrent Laryngeal Nerve Palsy
  • Recurrent Laryngeal Nerve Injuries

Interventions

DIAGNOSTIC_TEST

Point-of-Care Ultrasound of the Airway

Patients who are recruited will have an ultrasound performed of their larynx while they are on noninvasive positive pressure ventilation and then a second ultrasound when they are removed from noninvasive positive pressure ventilation. Between the two ultrasounds, the otolaryngology team will perform their fiberoptic nasolaryngoscopy, as per standard unit protocol and patient care.

Sponsors & Collaborators

  • Nemours Children's Clinic

    lead OTHER

Eligibility

Min Age
1 Day
Max Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-03-30
Primary Completion
2028-03-30
Completion
2028-05-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06406725 on ClinicalTrials.gov