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Intraocular Pressure During Prone Spinal Surgery

NCT00176722 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 7

Last updated 2015-04-24

No results posted yet for this study

Summary

Postoperative visual loss resulting from surgical procedures not performed on the eye is a devastating outcome for the patient and poorly understood by the medical community. It is potentially a preventable complication. Diminished blood supply to the optic nerve, affecting both the anterior or posterior portions of the optic nerve, is the most common cause of postoperative visual loss. Other, less common causes include occlusion of the retinal artery and vein, a retinal embolism and cortical blindness. The incidence of postoperative visual loss increases in patients undergoing cardiopulmonary bypass and prone spinal surgery. Although the etiology of postoperative visual loss is unknown, it is thought to be multifactorial, and several potential risk factors have been identified, including degree of low blood pressure, preoperative hematocrit, external compression of the eye, amount of blood loss, prolonged duration of surgical time and lying in the face down position. The investigators believe this study is a unique opportunity to examine the mechanisms responsible for the antecedents to postoperative visual loss (POVL) and ischemic optic neuropathy (ION), a devastating complication of (usually) an elective surgical procedure. The purpose of this research is to try and determine the potential variables responsible for postoperative visual loss which will assist the medical community in devising methods for its prevention.

Conditions

  • Spine Surgery
  • Vision Impairment

Interventions

OTHER

table tilt

One group randomized to table tilt. One group will be flat.

Sponsors & Collaborators

  • Foundation for Anesthesia Education and Research

    collaborator OTHER

  • New Jersey Eye Institute

    collaborator UNKNOWN

  • University of Medicine and Dentistry of New Jersey

    lead OTHER

Principal Investigators

  • Geordie Grant, MD · Rutgers, The State University of New Jersey

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-06-30
Primary Completion
2011-10-31
Completion
2012-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00176722 on ClinicalTrials.gov