Low Birthweight and Preterm Infant Feeding Trial and Supportive Care Package: Implementation Research

Summary

Low Birthweight and Preterm Infant Feeding Trial and Supportive Care Package (LIFT-UP) aims to improve feeding and growth outcomes among low birthweight (LBW; \<2.5kg) or preterm (\<37 weeks gestational age) infants admitted to neonatal intensive care units (NICU) in India, Malawi, and Tanzania by (1) supporting the initiation, establishment, and maintenance of maternal lactation and prioritized provision of human milk, Kangaroo Mother Care (KMC) and appropriate water, sanitation and hygiene (WASH) practices; and (2) facilitating feeding counseling at home post-discharge from the facility.

Conditions

• Low Birthweight
• Preterm Birth

Interventions

OTHER

Facility-based feeding support package plus (FB-FSP+)

Package of materials to support facility-based feeding and lactation, KMC and WASH, including a training curriculum, training guide, and implementation materials, such as Standard Operating Procedures (SOPs) and job aides

OTHER

Transition-to-home feeding support package plus (TTH-FSP+)

Package of materials to support transition-to-home feeding and lactation, KMC and WASH, including a training curriculum, training guide, and implementation materials, such as Standard Operating Procedures (SOPs) and job aides

Sponsors & Collaborators

• Boston Children's Hospital

  collaborator OTHER

• Community Empowerment Lab

  collaborator OTHER

• Emory University

  collaborator OTHER

• Muhimbili University of Health and Allied Sciences

  collaborator OTHER

• Jawaharlal Nehru Medical College

  collaborator OTHER

• PATH

  collaborator OTHER

• University of North Carolina

  collaborator OTHER

• Brigham and Women's Hospital

  collaborator OTHER

• Harvard School of Public Health (HSPH)

  lead OTHER

Principal Investigators

• Katherine Semrau, PhD, MPH · Ariadne Labs

Study Design

Allocation

NA

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

1 Minute

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2024-05-08

Primary Completion

2026-02-13

Completion

2026-02-13

Countries

• India
• Malawi
• Tanzania

Study Locations