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Radiotherapy Treatment Planning Comparison Using SBRT-PATHY (Photons) Versus CARBON-PATHY for Unresectable Bulky Tumors

NCT06390657 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2025-05-11

No results posted yet for this study

Summary

This study uses a novel unconventional radiotherapy technique, consisting of high dose PArtial Tumor irradiation targeting exclusively the HYpoxic segment of unresectable bulky tumors delivered either with photons (SBRT-PATHY) or with carbon-ions (CARBON-PATHY) while sparing the peritumoral immune microenvironment (PIM).

Conditions

Interventions

OTHER

Planning CT, MRI

SBRT-PATHY and CARBON-PATHY planning is performed for study purposes only. Patients will be treated according to standard radiotherapy as per institutional policies. The planning images (CT, MRI) will be anonymized and used for planning purposes only.

Sponsors & Collaborators

  • The Princess Margaret Cancer Foundation

    collaborator OTHER

  • EBG MedAustron GmbH

    lead INDUSTRY

Principal Investigators

  • Slavisa Tubin, M.D. · EBG MedAustron

  • Rebecca Wong, MBChB, FRCPC, MSc, Prof. · Princess Margaret Cancer Centre

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-06-30
Primary Completion
2025-12-31
Completion
2025-12-31

Countries

  • Austria

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06390657 on ClinicalTrials.gov