Physical Activity, Sleep and Brain Health Based on the Glymphatic System

NCT06378515 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 77

Last updated 2024-08-13

No results posted yet for this study

Summary

This study is aiming to analyze the impact of physical activity on neurohydrodynamics and glymphatic activity on young adults. This study is designed as a multicenter descriptive observational study with information collection at two different times: before performing a short exercise routine and during its performance using a wearable wireless device Glymphometer.

Conditions

  • Brain Diseases

Interventions

OTHER

Physical activity, postural changes and cognitive tasks

1. Measuring while patients are sitting in rest for 5 minutes. 2. Supine to stand test: lying down (5 min) standing up (5 min) 3. Repeated sit stand test: sitting (10 sec) ↔ standing (10 sec), changing position every 10 seconds for 5 minutes. 4. Paced breathing in sitting position: letting patients breath 6 breaths/minute (0.1Hz) for 5 minutes. 5. Breath hold manoeuvre in sitting position: 60s normal breathing, then 32s breath hold + 88s normal breathing repeated 3 times. 6. Arithmetic stress test by giving the subject single digit addition. To give the pressure, subject needs to do as many as possible calculation within 1 minute with 1 minute break. This is repeated 3 times.

Sponsors & Collaborators

  • University of Oulu

    collaborator OTHER
  • University of Valencia

    lead OTHER

Principal Investigators

  • Raquel Faubel, PhD · Universitat de València

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-05-01
Primary Completion
2025-04-30
Completion
2025-12-31

Countries

  • Spain

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06378515 on ClinicalTrials.gov