Multi-omics Characteristics and Prognosis of Idiopathic Sudden Sensorineural Hearing Loss
NCT06365775 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 400
Last updated 2024-04-15
Summary
The goal of this observational study is to describe the multi-omics characteristics and to learn about the prognostic factors in patients with idiopathic sudden sensorineural hearing loss (SSNHL). The main problems it aims to deal with are:
* if there is a difference in data of exome and targeted sequencing among patients with SSNHL affecting bilateral and unilateral sides, and healthy controls
* if there is a difference in the parameter of MRI among patients with SSNHL affecting bilateral and unilateral sides, and healthy controls
* to find out which factor from multi-omics data relates to outcomes of SSNHL
* to develop the best prognostics model based on the multi-omics data.
Participants will be received audiological tests, blood specimen collection and radiological examination. Researchers will explore the relationship between the multi-omics data and the prognosis and develop the predictive model.
Conditions
- Sudden Sensorineural Hearing Loss
- Hearing Loss, Sensorineural
- Hearing Loss, Sudden
Sponsors & Collaborators
-
Dan Bing
lead OTHER
Eligibility
- Min Age
- 4 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-04-23
- Primary Completion
- 2026-11-23
- Completion
- 2026-11-23
More Related Trials
-
Development of Functional Spatial Hearing in Reverberation
NCT05815537 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Natural History in Children up to 16 Years With Mild to Profound Hearing Loss Due to Mutations in GJB2 / OTOF Genes
NCT05402813 ·Status: RECRUITING
-
Use of Functional Near-infrared Spectroscopy to Investigate Role of Human Auditory Cortex Plasticity and Multi-sensory Integration on Cochlear Implant Performance After Single-sided Deafness
NCT03713554 ·Status: WITHDRAWN
-
Quantification of Visually Evoked Cortical Potentials in Individuals With Hearing Loss
NCT05107466 ·Status: RECRUITING
-
Cohort Of DEafness-gene Screening
NCT06133946 ·Status: ACTIVE_NOT_RECRUITING
-
Functioning, Disability, and Quality of Life in the Adult Hearing Impaired
NCT00037986 ·Status: COMPLETED ·Phase: PHASE2
-
Auditory Neural Function in Implanted Patients With Usher Syndrome
NCT04906135 ·Status: COMPLETED ·Phase: NA
-
Localization and Mismatch Negativity
NCT03632551 ·Status: UNKNOWN ·Phase: NA
-
Inventory of Radiological and Vestibular Function in Cochlear Implant Candidates
NCT04066270 ·Status: UNKNOWN
-
Dual-Task Cost in Bilateral Hearing Loss
NCT05540535 ·Status: COMPLETED
-
Development Cellular Models of the Ear and Nose to Study the Mechanisms of Hearing
NCT04823195 ·Status: UNKNOWN
-
Correlation Between Prognosis of Mild Cognitive Impairment and Hearing Function in Community Elderly
NCT05336942 ·Status: COMPLETED
-
Speech Perception Impairment Follow Complete Recovery of Sudden Sensorineural Hearing Loss
NCT05608161 ·Status: UNKNOWN
-
Societal Merit of Intervention on Hearing Loss Evaluation
NCT05525221 ·Status: RECRUITING
-
Functional Near Infra-Red Spectroscopic Study of Central Auditory System Cortical Functional Reorganization
NCT04043910 ·Status: COMPLETED ·Phase: NA
-
Cross-sectional and Prospective Study to Characterize Early-onset Presbycusis
NCT06354010 ·Status: RECRUITING
-
Association Between Severe-to-profound Hearing Loss and the Balance Function of the Inner Ear
NCT05500521 ·Status: COMPLETED
-
Sensory Integration of Auditory and Visual Cues in Diverse Contexts
NCT04479761 ·Status: COMPLETED ·Phase: NA
-
Early Detection of Noise-Induced Hearing Loss
NCT01022710 ·Status: WITHDRAWN
-
Variability In Hearing Aid Outcomes In Older Adults
NCT02448706 ·Status: COMPLETED ·Phase: NA
-
Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces
NCT05867173 ·Status: RECRUITING ·Phase: NA
-
Improving Early Intervention in Hearing Impaired Children Using Functional Near-Infrared Spectroscopy (fNIRS)
NCT05847426 ·Status: RECRUITING ·Phase: NA
-
Cognitive Screening of Patients with Hearing Loss
NCT04672174 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
The Contributions of Age Related Changes in the Sound Localization Pathway to Central Hearing Loss
NCT04513782 ·Status: RECRUITING
-
Electrophysiological Study of Interindividual Differences in Speech-understanding Among Cochlear Implant Patients
NCT01805167 ·Status: UNKNOWN ·Phase: NA