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External Validation of Simplified 4C Mortality Score by Deleting CRP

NCT06354946 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1500

Last updated 2024-04-09

No results posted yet for this study

Summary

The (Coronavirus Clinical Characterisation Consortoum) 4C mortality score is an accessible risk stratification score developed by the International Severe Acute Respiratory and Emerging Infections Consortium (ISARIC) based on eight different parameters: age, sex, number of comorbidities, respiratory rate, peripheral oxygen saturation, level of consciousness (Glasgow Coma Scale), urea or blood urea nitrogen (BUN) level, and C reactive protein (CRP). It was derived and internally validated on a large, diverse cohort within the United Kingdom but requires external validity to confirm its generalizability. A recent validation study demonstrated that the score could be simplified by deleting CRP item which is favorable to its widespread use. we aim to validate a modified 4C score.

Conditions

  • COVID-19 Pandemic

Sponsors & Collaborators

  • University of Monastir

    lead OTHER

Principal Investigators

  • Khaoula Bel Haj Ali · CHU Fattouma Bourguiba Monastir, service des urgences

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2020-01-01
Primary Completion
2022-11-30
Completion
2022-12-30

Countries

  • Tunisia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06354946 on ClinicalTrials.gov