Albumin Utilization in Adult Cardiac Surgical Patients: Retrospective
NCT06322537 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 505
Last updated 2025-11-26
Summary
All heart surgery patients universally require hydration, which is given through a vein in the arm, but practices for treating patients are not universal. There are disagreements about whether crystalloids should be used alone or in combination with albumin. This question has important implications because albumin is an expensive blood product in relatively limited supply, and 20% of its use is by heart surgery patients. The goal of this study is to learn more about how crystalloids and albumin are used during heart surgery, as well as, key patient outcomes.
Conditions
- Cardiovascular Surgical Procedures
- Albumin
Sponsors & Collaborators
-
Kingston Health Sciences Centre
collaborator OTHER -
Unity Health Toronto
collaborator OTHER - collaborator OTHER
-
Sunnybrook Health Sciences Centre
collaborator OTHER -
London Health Sciences Centre
collaborator OTHER -
The Ottawa Hospital
collaborator OTHER -
Vancouver General Hospital
collaborator OTHER -
Royal Columbian Hospital Foundation
collaborator OTHER -
Nova Scotia Health Authority
collaborator OTHER -
University Health Network, Toronto
lead OTHER
Principal Investigators
-
Keyvan Karkouti, MD MSc FRCPC · Toronto General Hospital - University Health Network
Eligibility
- Min Age
- 18 Years
- Max Age
- 99 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-05-23
- Primary Completion
- 2025-12-01
- Completion
- 2026-01-01
Countries
- Canada
Study Locations
More Related Trials
-
Acute Normovolemic Hemodilution on Serum-creatinine Concentration in Cardiac Surgery
NCT02831270 ·Status: COMPLETED
-
Limiting IV Chloride to Reduce AKI After Cardiac Surgery
NCT02020538 ·Status: COMPLETED ·Phase: NA
-
Relationship of Point-of-care Coagulation Assays with Clinical Outcomes in Cardiac Surgery: a Retrospective Cohort Study
NCT06882759 ·Status: NOT_YET_RECRUITING
-
Perioperative Risk Factors of Outcomes for Cardiac Surgery: A Retrospective Study
NCT04980742 ·Status: UNKNOWN
-
The Effect of Washing Red Blood Cells on Post Heart Surgery Blood Loss
NCT00624611 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Decreased Pump Prime Volume on Blood Transfusions and Postoperative Complications of Patients Undergoing High Risk Cardiac Surgical Procedures
NCT00646373 ·Status: TERMINATED ·Phase: NA
-
Fluid Balance and Clinical Outcomes
NCT01168583 ·Status: COMPLETED
-
Evaluation of Different Priming Solutions Effects on Microcirculation, Oxidative Stress and Morbidity in Cardiovascular Surgery Patients
NCT02501681 ·Status: COMPLETED ·Phase: PHASE4
-
Hyponatremia and Hypoalbuminemia is Morbimortality Predictors in Coronary Artery Bypass Graft Surgery
NCT02765061 ·Status: COMPLETED
-
Perioperative Reduction of Inapparent Myocardial Injury
NCT01850927 ·Status: COMPLETED ·Phase: NA
-
The Protection of ACD III on Erythrocytes in Intraoperative Blood Salvage During Cardiopulmonary Bypass
NCT05267145 ·Status: UNKNOWN ·Phase: NA
-
Acute Normovolemic Hemodilution on ROTEM in Cardiac Surgery
NCT02502448 ·Status: COMPLETED ·Phase: NA
-
Preventing Myocardial Ischemia by Preconditioning in Elective Operation for Abdominal Aortic Aneurysm
NCT01523262 ·Status: UNKNOWN ·Phase: PHASE1
-
Impact of Fluid Resuscitation Protocol on the Incidence of Reoperation for Bleeding After Emergency Cardiopulmonary Bypass Grafting
NCT04533698 ·Status: COMPLETED
-
Hyperbilirubinemia After Cardiac Surgery
NCT01617902 ·Status: UNKNOWN
-
Transfusion Requirements in Cardiac Surgery
NCT01484639 ·Status: COMPLETED ·Phase: NA
-
Hemodilution and Outcome in Cardiac Surgery
NCT00364494 ·Status: TERMINATED ·Phase: NA
-
Fluid Infusion During Breast Surgery
NCT00431743 ·Status: UNKNOWN ·Phase: PHASE4
-
Erythrocyte Transfusion Based on the Measurement of Central Venous Oxygen Saturation in Postoperative Cardiac Surgery
NCT02963883 ·Status: COMPLETED ·Phase: NA
-
Remote Ischemic Preconditioning in Cardiac Surgery Trial
NCT01071265 ·Status: COMPLETED ·Phase: NA
-
Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery
NCT03684876 ·Status: UNKNOWN
-
Hydration During Thoracic Surgery
NCT04817722 ·Status: COMPLETED
-
Blood Volume and Fluid Kinetics in Patients Undergoing Extracorporal Circulation
NCT01115166 ·Status: COMPLETED
-
Optimization of Prime Fluid Strategy to Preserve Microcirculatory Perfusion During Cardiac Surgery With Cardiopulmonary Bypass, Part II
NCT05647200 ·Status: UNKNOWN ·Phase: NA
-
Venous Congestion and Cardiac Surgery-Associated Acute Kidney Injury
NCT07232277 ·Status: RECRUITING