Retinal Vascular Changes During Pregnancy
NCT06311617 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 90
Last updated 2026-05-08
Summary
The goal of this study is to better understand how the back part of the eye-called the retina and the choroid-changes during pregnancy. Specialized photos of the eye will be taken at three different timepoints: early in pregnancy (first or second trimester), late in pregnancy (third trimester), and after delivery. This imaging is non-invasive and does not require contact with the surface of the eye. The photos taken will allow assessment of specific parameters, like blood flow and the health of specialized cells that support vision. Understanding how the eyes change during pregnancy may help guide how retina specialists understanding of retinal disease during pregnancy and better inform pregnancy outcomes.
Conditions
- Pregnancy
Interventions
- DIAGNOSTIC_TEST
-
Optical coherence tomography
Non-mydriatic fundus photography and optical coherence tomography will be performed at 3 timepoints
Sponsors & Collaborators
-
Vanderbilt University Medical Center
lead OTHER
Principal Investigators
-
Avni P Finn, MD, MBA · Vanderbilt Eye Institute
Eligibility
- Min Age
- 18 Years
- Sex
- FEMALE
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2024-02-01
- Primary Completion
- 2027-01-31
- Completion
- 2027-01-31
Countries
- United States
Study Locations
More Related Trials
-
Prediction of Outcome in Severe Preeclampsia
NCT03871764 ·Status: COMPLETED
-
Combined 3D Power Doppler Placental Volume and Vascular Flow Indices In the First Trimester of Pregnancy as Predictors Of Preeclampsia?.
NCT03399006 ·Status: UNKNOWN
-
Evaluation of Pre-dose and Post-dose Anti-factor Xa Levels With Enoxaparin Use During Pregnancy
NCT00319176 ·Status: COMPLETED
-
Utero-placental Vascularisation in Normal and Preeclamptic and Intra-uterine Growth Restriction Pregnancies
NCT02825277 ·Status: UNKNOWN ·Phase: NA
-
Study of the Involvement of Fatty Acids in Retinopathy of Prematurity: Relationship Between Retinopathy of Prematurity and the Rate of Expression of Transplacental Fatty Acid Receptors.
NCT04819893 ·Status: RECRUITING
-
Predicting Placental Pathologies by Ultrasound Imaging
NCT04506970 ·Status: COMPLETED
-
Effects of Retinoids on CYP2D6 Activity During Pregnancy
NCT03117660 ·Status: COMPLETED ·Phase: PHASE1
-
Fetal Renal Artery Doppler in Patients With Preeclampsia
NCT06395974 ·Status: COMPLETED
-
Diagnostic Performance of Antenatal Ultrasound for High-Risk Intestinal Malrotation
NCT03968107 ·Status: TERMINATED
-
Prevalence of Ambivalence Regarding Prenatal Testing
NCT00342069 ·Status: COMPLETED
-
Early Pregnancy Evaluation by Three-Dimensional Ultrasound
NCT00342290 ·Status: TERMINATED
-
Microcirculatory and Tissue and Cerebral Oxygenation in Preeclampsia and Normal Pregnancy: An Observation Study
NCT02351583 ·Status: WITHDRAWN
-
Vascular Changes in Pre-Eclamptic Patients and Its Impact on Pregnancy Outcome.
NCT03111576 ·Status: UNKNOWN
-
Evaluation of Novel Point of Care Coagulation System in Pregnant Women
NCT04301193 ·Status: COMPLETED
-
Assessment of the Number of Umbilical Cord Vessels at the Time of Nuchal Translucency Screening
NCT01367132 ·Status: COMPLETED
-
Placental Vasculature for Prediction of Recurrent Fetal Growth Restriction
NCT04399174 ·Status: COMPLETED
-
Non Invasive Prenatal Testing (NIPT) of Single-gene Disorders
NCT02339402 ·Status: UNKNOWN
-
Fetal Doppler Indices in Predicting Perinatal Outcome Among Severely Hypertensive Pregnant Patients.
NCT03515759 ·Status: COMPLETED
-
Development of Non-invasive Prenatal Screening Test for Microdeletions Based on Fetal DNA Isolated From Maternal Blood
NCT01852708 ·Status: COMPLETED
-
Maternal Uterine Artery Doppler Study
NCT01698957 ·Status: COMPLETED
-
MRI Angiography of Physiological and Pathological Pregnancy Placentas Ex-vivo
NCT04389099 ·Status: COMPLETED
-
A Clinical Study of Fundus Findings in Toxaemia of Pregnancy
NCT03076619 ·Status: COMPLETED
-
Non-invasive Placental Chromosome Exploration of Intrauterine Growth Restriction
NCT05023161 ·Status: RECRUITING
-
Development of a Non-invasive Prenatal Test
NCT01451684 ·Status: COMPLETED
-
Observational Study in UTERO - Placental 3D Doppler Examination: Interest for Pre-eclampsia Screening During Pregnancy
NCT00930397 ·Status: COMPLETED