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Detection of Aneuploidy in Cell Free DNA to Improve the Sensitivity of Diagnostic Peritoneal Lavage in Gastric Cancer

NCT06308510 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 63

Last updated 2025-02-25

No results posted yet for this study

Summary

Aneuploidy may be used as a more sensitive diagnostic tool to detect peritoneal metastasis compared to conventional cytology and imaging techniques. Our aim is to establish whether aneuploidy as detected in cfDNA (as a measure for ctDNA) in PLF of patients with GC may hold value as an additional staging and tumor evaluation method in GC patients.

Conditions

Interventions

OTHER

collection additional peritoneal lavage fluid

collection additional peritoneal lavage fluid

Sponsors & Collaborators

Principal Investigators

  • Bianca Mostert, MD · Erasmus Medical Center

  • Sjoerd Lagarde, MD · Erasmus Medical Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-12-17
Primary Completion
2026-07-31
Completion
2028-07-31

Countries

  • Netherlands

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06308510 on ClinicalTrials.gov