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Ultra-high-caloric, Fatty Diet in ALS

NCT06280079 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 392

Last updated 2026-05-01

No results posted yet for this study

Summary

This study aims at evaluating efficacy and tolerability of an ultra-high-caloric, fatty diet (UFD) compared to placebo in patients with amyotrophic lateral sclerosis (ALS).

Conditions

Interventions

DIETARY_SUPPLEMENT

Ultra-high-caloric fatty diet

100% fat (70g), saturated fatty acids 7,5g, monounsaturated fatty acids 42,6g, polyunsaturated fatty acids 19,9g, long-chain fatty acids 100%, ratio omega-6 to omega-3 fatty acids 5:1, protein 0g, carbohydrates 0g, fiber 0g

OTHER

Placebo

\<5% fat (\<3,5g), protein 0g, carbohydrates 0g, fiber 0g

Sponsors & Collaborators

  • University of Ulm

    lead OTHER

Principal Investigators

  • Johannes Dorst, Prof. Dr. · University of Ulm

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-06-01
Primary Completion
2028-01-01
Completion
2028-01-01

Countries

  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06280079 on ClinicalTrials.gov