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A Prospective Study on the Treatment of cLM Based on ICG Imaging

NCT06275022 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 110

Last updated 2026-02-18

No results posted yet for this study

Summary

The goal of this prospective randomized controlled study is to explore the role of indocyanine green-fluorescence imaging in management of cystic lymphatic malformation.. To clarify the application value of indocyanine green-fluorescence imaging in both diagnosis and treatment of cystic lymphatic malformation (cLM) in children, is helpful for exploring pathogenesis of cLM, and providing a clearer scientific basis for subsequent surgical intervention. It also provides alternative for the future diagnosis and treatment of cLM.

Participants will receive indocyanine green-fluorescence imaging before operation, while the patients in control group will receive traditional operation.

Researchers will compare difference in curative effect between two groups.

Conditions

  • Lymphatic Malformation

Interventions

PROCEDURE

Inflow occlusion with perforation of septation and sclerotherapy

Inflow occlusion assisted by indocyanine green-fluorescence imaging combined with perforation of septation and sclerotherapy

PROCEDURE

Perforation of septation and sclerotherapy

Perforation of septation and sclerotherapy

PROCEDURE

Indocyanine green-guided partial resection and sclerotherapy

Indocyanine green-fluorescence imaging-guided partial resection and sclerotherapy

PROCEDURE

Partial resection and sclerotherapy

Partial resection and sclerotherapy

Sponsors & Collaborators

  • Nanjing Children's Hospital

    lead OTHER

Principal Investigators

  • Weimin Shen, Dr. · Children's Hospital of Nanjing Medical University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
30 Days
Max Age
16 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-01-01
Primary Completion
2026-03-20
Completion
2026-03-30

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06275022 on ClinicalTrials.gov