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Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery

NCT06255457 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2025-09-11

No results posted yet for this study

Summary

Study objectives:

* To assess the impact of mitral valve surgery for mitral regurgitation on ventricular arrhythmic burden and surrogate markers of fibrosis in patients with arrhytmogenic mitral valve prolapse (MVP) from baseline to 6 months after surgery
* To characterize the molecular landscape of arrhytmogenic MVP

Study design:

-Prospective explorative observational study

Study population:

-90 patients with arrhytmogenic MVP and without arrhytmogenic MVP (controls) eligible for mitral valve surgery for mitral regurgitation will be enrolled. All patients will be evaluated with cardiac magnetic resonance (CMR) imaging and continuous seven day arrhythmic monitoring before and at 6 months after mitral valve surgery

Conditions

  • Mitral Regurgitation
  • Mitral Valve Prolapse
  • Ventricular Tachycardia

Interventions

PROCEDURE

Mitral valve surgery

Mitral valve repair or replacement of mitral regurgitation

Sponsors & Collaborators

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-02-21
Primary Completion
2026-03-01
Completion
2026-03-01

Countries

  • Sweden

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06255457 on ClinicalTrials.gov