Dynamic Changes in Human Microbiome Predict the Risk of Adverse Outcomes in Patients With Acute Ischemic Stroke: a Multicenter Prospective Cohort Study
NCT06240468 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000
Last updated 2024-02-05
Summary
(1) The main purpose
To explore the predictive value of human microbiome and its metabolome for adverse prognosis in patients with acute ischemic stroke (AIS).
(2) Secondary purposes
1. To explore the characteristics of cross-regional disturbance of human microbiome in stroke patients;
2. To investigate the characteristics and rules of bacterial flora changes before and after recurrent apoplexy;
3. Markers closely related to AIS prognosis and cognitive emotional complications were excavated by metagenomic, metabolic, peptide and imaging groups.
4. To explore the relationship between serum markers of ultra early stage and prognosis.
Conditions
- Acute Ischemic Stroke
Interventions
- OTHER
-
not have
not have
Sponsors & Collaborators
-
Zhujiang Hospital
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 80 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2022-02-10
- Primary Completion
- 2024-12-30
- Completion
- 2025-12-30
Countries
- China
Study Locations
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