Intensive Postpartum Antihypertensive Treatment
NCT05687344 · Status: ACTIVE_NOT_RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2025-10-23
Summary
The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.
Conditions
- Hypertensive Disorder of Pregnancy
Interventions
- DRUG
-
Nifedipine ER
Postpartum BP treatment to \<140/90 mmHg
Sponsors & Collaborators
-
Medical College of Wisconsin
lead OTHER
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-09-01
- Primary Completion
- 2026-03-31
- Completion
- 2026-03-31
- FDA Drug
- Yes
Countries
- United States
Study Locations
More Related Trials
-
Effect of Labetalol, Atenolol, and Nifedipine on Maternal Hemodynamics Measured by ICG in Early Pregnancy
NCT04755764 ·Status: RECRUITING
-
Persistent Postpartum Hypertension Pilot Trial
NCT04349124 ·Status: TERMINATED ·Phase: PHASE4
-
Prevention of Severe Postpartum Hypertension
NCT02450773 ·Status: WITHDRAWN ·Phase: PHASE2
-
Postpartum Hypertension, Tight vs Liberal Control Trial
NCT04592783 ·Status: COMPLETED ·Phase: NA
-
Hypertension In Postpartum Preeclampsia Study
NCT03011567 ·Status: COMPLETED ·Phase: NA
-
Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy
NCT01912677 ·Status: COMPLETED ·Phase: PHASE4
-
Innovation in Postpartum Care for Women With Hypertensive Disorders of Pregnancy
NCT03613714 ·Status: COMPLETED ·Phase: NA
-
Optimal Blood Pressure Treatment Thresholds Postpartum
NCT06069102 ·Status: COMPLETED ·Phase: PHASE4
-
Postpartum Evaluation of Nifedipine and Enalapril for Hypertension
NCT07023003 ·Status: RECRUITING ·Phase: PHASE4
-
Swiss Postpartum Hypertension Cohort
NCT04690660 ·Status: RECRUITING
-
Oral Nifedipine Versus Labetalol in Treatment of Postpartum Hypertension
NCT03449277 ·Status: UNKNOWN ·Phase: PHASE4
-
Sensitivity of Angiotensin II Type II Receptors in Women Following Preeclampsia
NCT05937841 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Women Specific Cardiac Recovery After Preeclampsia
NCT02807324 ·Status: UNKNOWN
-
Furosemide for Accelerated Recovery of Blood Pressure Postpartum
NCT03556761 ·Status: COMPLETED ·Phase: PHASE2
-
Impedance Cardiography to Decrease the Risk of Preeclampsia
NCT03245970 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
Management of Hypertension in the Early Postpartum: a Randomized Controlled Trial
NCT04835233 ·Status: COMPLETED ·Phase: PHASE4
-
Clinical Outcomes of NovoSeven® Treatment in Severe Postpartum Haemorrhage - a Study at the University Hospital of Bern
NCT04444856 ·Status: COMPLETED
-
Exercise Testing After Preeclampsia
NCT06741436 ·Status: RECRUITING
-
Treatment Targets for Chronic Hypertension in Pregnancy
NCT00194974 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Comparison of Tab.Labetalol and Tab.Nifedipine for Management of Postpartum Hypertension
NCT02426177 ·Status: UNKNOWN ·Phase: PHASE3
-
A Research Study to See How Safe is Eptacog Alfa When Used to Stop Heavy Bleeding in Women After Giving Birth in India
NCT07157423 ·Status: RECRUITING ·Phase: PHASE4
-
Hypertension Explored in Long-term Postpartum Follow-up in Later Life
NCT06187012 ·Status: RECRUITING
-
Safest Choice of Antihypertensive Regimen for Postpartum Hypertension
NCT05551104 ·Status: RECRUITING ·Phase: PHASE3
-
Vascular Effects of High-Salt After Preeclampsia
NCT06749418 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Comprehensive Postpartum Management for Women With Hypertensive Disorders of Pregnancy
NCT05849103 ·Status: COMPLETED ·Phase: NA