MDS

Disease

Disease Profile

MDS most commonly refers to myelodysplastic syndromes, a group of clonal myeloid malignancies characterized by ineffective hematopoiesis and peripheral blood cytopenias. These syndromes may progress to acute myeloid leukemia in a subset of patients.

Category
hematologic malignancy
Prevalence
In the United States, slightly more than 10,000 people are diagnosed with MDS yearly, with annual age-adjusted incidence around 4.4 to 4.6 per 100,000.

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Related Clinical Trials

NCT ID Title Status Phase
NCT07702578

A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation

RECRUITING PHASE3
NCT07575412

SHR2554/AZA + Overlapped Modified BUCY for High-risk/Relapsed Leukemia/MDS

NOT_YET_RECRUITING PHASE2
NCT07562568

SHR2554/AZA + Overlapped TBF for High-risk/Relapsed Leukemia/MDS

NOT_YET_RECRUITING PHASE2
NCT07493538

MT2025-35 Allogeneic Hematopoietic Stem Cell Transplantation Using Reduced Intensity Conditioning Treosulfan and Fludarabine, With Post-Transplant Cytoxan (PTCy) for the Treatment of Hematological Diseases

RECRUITING PHASE2
NCT07387354

Pacritinib With Aza for Upfront Myelodysplastic Syndrome

WITHDRAWN PHASE1/PHASE2
NCT07347171

A Phase 1 Study of CG009301 for Injection in Adult Subjects With Recurrent or Refractory Haematological Malignancies

RECRUITING PHASE1
NCT07328191

Quality of Life-Guided Transfusion in Refractory MDS or AML

RECRUITING NA
NCT07318662

Efficacy and Safety of HMAs Combined With Venetoclax Versus HMAs Alone in ND Int-and H-risk MDS or CMML

ACTIVE_NOT_RECRUITING
NCT07205523

High-Altitude Hematology Observation-Stem Cell Transplantation (HALO-SCT)

RECRUITING
NCT07131085

QH101 Cell Therapy Relapsed/Refractory(R/R) Acute Myeloid Leukemia(AML) and Myelodysplastic Syndromes(MDS)

NOT_YET_RECRUITING PHASE1