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Deep Functional Phenotyping of the ALA Lung Health Cohort

NCT06177717 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2026-03-06

No results posted yet for this study

Summary

The goal of this observational study is to learn about lung structure and function in a group of 1000 healthy people aged 25 to 35. The main questions it aims to answer are whether people's bodies, environment, and general lung health are associated with:

* the structure of the participants lungs' airways,
* the structure of blood vessels in the participants lungs and heart, and
* the participants lungs' ability to exchange gases.

Participants will take four different lung function tests to measure lung function, including:

* air movement in the lungs (oscillometry)
* lung size (slow vital capacity (SVC) and functional residual capacity (FRC)
* gas transfer in the lungs (diffusing capacity for carbon monoxide (DLCO).

Conditions

  • Lung Diseases

Sponsors & Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

    collaborator NIH

  • American Lung Association

    collaborator OTHER

  • University of Vermont

    collaborator OTHER

  • Johns Hopkins University

    lead OTHER

Principal Investigators

  • Meredith McCormack, MD · Johns Hopkins University

Eligibility

Min Age
25 Years
Max Age
35 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-02-12
Primary Completion
2026-07-30
Completion
2026-07-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06177717 on ClinicalTrials.gov